Myogenic Progenitor Cells Exhibit Type I Interferon –Driven Proangiogenic Properties and Molecular Signature During Juvenile Dermatomyositis

ConclusionThese results demonstrate a new type I IFN pathway in JDM that activates the production of angiogenic effectors by MPCs, triggering their proangiogenic function to promote vessel recovery and muscle reconstruction.

Source: Arthritis and Rheumatism - November 28, 2017 Category: Rheumatology Authors: Cyril Gitiaux, Claire Latroche, Mich èle Weiss‐Gayet, Mathieu P. Rodero, Darragh Duffy, Brigitte Bader‐Meunier, Christophe Glorion, Patrick Nusbaum, Christine Bodemer, Guy Mouchiroud, Jamel Chelly, Stéphane Germain, Isabelle Desguerre, Bénédicte C Tags: Original Article Source Type: research