Radionuclide Imaging of Infection and Inflammation in Children: a Review

With the exception of radiolabeled monoclonal antibodies, antibody fragments and radiolabeled peptides which have seen little application in the pediatric population, the nuclear medicine imaging procedures used in the evaluation of infection and inflammation are the same for both adults and children. These procedures include (1) either a two- or a three-phase bone scan using technetium-99m methylene diphosphonate; (2) Gallium 67-citrate; (3) in vitro radiolabeled white blood cell imaging (using 111Indium-oxine or 99mTechnetium hexamethyl-propylene-amine-oxime –labeled white blood cells); and (4) hybrid imaging with 18F-FDG.
Source: Seminars in Nuclear Medicine - Category: Nuclear Medicine Authors: Source Type: research