Organocatalytic Atroposelective Arylation of 2 ‐Naphthylamines as a Practical Approach to Axially Chiral Biaryl Amino Alcohols

AngewchemOrganocatalytic Atroposelective Arylation of 2 ‐Naphthylamines as a Practical Approach to Axially Chiral Biaryl Amino Alcohols: The first phosphoric acid catalyzed direct arylation of 2 ‐naphthylamines with iminoquinones for the atroposelective synthesis of axially chiral biaryl amino alcohols has been developed. This reaction constitutes...

Source: Organometallic Current - November 28, 2017 Category: Chemistry Tags: Arylation chiral organocatalysis Source Type: blogs