Ligand ‐controlled Regiodivergent C−H Alkenylation of Pyrazoles and its Application to the Synthesis of Indazoles

AngewchemLigand ‐controlled Regiodivergent C−H Alkenylation of Pyrazoles and its Application to the Synthesis of Indazoles: Regioselective C4 ‐, C5‐, and di‐alkenylations of pyrazoles were achieved. An electrophilic Pd catalyst generated by trifluoroacetic acid (TFA) and 4,5‐diazafluoren‐9‐one (DAF) leads to C4‐alkenylation,...

Source: Organometallic Current - November 28, 2017 Category: Chemistry Tags: C-H Alkenylation Pd Catalyzed Source Type: blogs