Trends in GPCR drug discovery: new agents, targets and indications

Nature Reviews Drug Discovery 16, 829 (2017).
doi:10.1038/nrd.2017.178

Authors: Alexander S. Hauser, Misty M. Attwood, Mathias Rask-Andersen, Helgi B. Schiöth & David E. Gloriam
G protein-coupled receptors (GPCRs) are the most intensively studied drug targets, mostly due to their substantial involvement in human pathophysiology and their pharmacological tractability. Here, we report an up-to-date analysis of all GPCR drugs and agents in clinical trials, which reveals current trends across molecule

Source: Nature Reviews Drug Discovery - October 27, 2017 Category: Drugs & Pharmacology Authors: Alexander S. Hauser Misty M. Attwood Mathias Rask-Andersen Helgi B. Schi ö th David E. Gloriam Tags: Analysis Source Type: research