GPCRs: Crystal structure of D4 dopamine receptor
Nature Reviews Drug Discovery 16, 828 (2017).
doi:10.1038/nrd.2017.236
Author: Sarah Crunkhorn
Numerous compounds are reported to interact with dopamine receptors, but the molecular mechanisms mediating dopamine receptor selectivity and activity are poorly understood. Here, Wang et al. determine crystal structures of the D4 dopamine receptor (D4R) in its inactive state bound to the
Source: Nature Reviews Drug Discovery - Category: Drugs & Pharmacology Authors: Sarah Crunkhorn Tags: Research Highlight Source Type: research
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