TRAF6 regulates proliferation of stromal cells in the transition and peripheral zones of benign prostatic hyperplasia via Akt/mTOR signaling

ConclusionsTRAF6 can promote the proliferation of stromal cells of BPH via Akt/mTOR signaling. Our results may make stromal TRAF6 responsible for zonal characteristic of BPH and as a promising therapeutic strategy for BPH treatment.

Source: The Prostate - November 24, 2017 Category: Urology & Nephrology Authors: Yun ‐Feng Shi, Dian‐Jun Yu, Chen‐Yi Jiang, Xing‐Jie Wang, Yi‐Ping Zhu, Rui‐Zhe Zhao, Zhong Lv, Xiao‐Wen Sun Tags: ORIGINAL ARTICLE Source Type: research