Cortisol profiles differentiated in adolescents and young adult males with fragile X syndrome versus autism spectrum disorder

ConclusionsTaken together, findings suggest a unique neuroendocrine profile that distinguishes adolescent/young adult males with FXS from those with non‐syndromic ASD. Severity of ASD symptoms appears to be related to cortisol reactivity in the non‐syndromic ASD sample, but not in FXS; while anxiety symptoms are associated with HPA activation in the FXS sample, but not in ASD despite a high prevalence of ASD, anxiety and physiological dysregulation characteristic in both populations.

http://onlinelibrary.wiley.com/resolve/doi?DOI=10.1002%2Fdev.21578

Source: Developmental Psychobiology - November 24, 2017 Category: Psychiatry & Psychology Authors: Sara M. Matherly, Jessica Klusek, Angela J. Thurman, Andrea McDuffie, Leonard Abbeduto, Jane E. Roberts Tags: RESEARCH ARTICLE Source Type: research