Low FoxG1 and high Olig ‐2 labelling indices define a prognostically favourable subset in isocitrate dehydrogenase (IDH)‐mutant gliomas

ConclusionsWhile the combined FoxG1/Olig‐2 profile may discriminate H3F3A K27‐ and G34‐mutant tumours and define a prognostically favourable subset in IDH‐mutant gliomas, our data show that labelling indices of these transcription factors overlap with adult IDH‐mutant and wild‐type tumour classes.

http://onlinelibrary.wiley.com/resolve/doi?DOI=10.1111%2Fnan.12447

Source: Neuropathology and Applied Neurobiology - November 23, 2017 Category: Neurology Authors: S. Sch äfer, F. Behling, M. Skardelly, M. Koch, I. Ott, F. Paulsen, G. Tabatabai, J. Schittenhelm Tags: Original Article Source Type: research