Increased cortical neuronal responses to NMDA and improved attentional set-shifting performance in rats following prebiotic (B-GOS ®) ingestion

We have previously shown that prebiotics (dietary fibres that augment the growth of indigenous beneficial gut bacteria) such as Bimuno ™ galacto-oligosaccharides (B-GOS®), increased N-methyl-D-aspartate (NMDA) receptor levels in the rat brain. The current investigation examined the functional correlates of these changes in B-GOS®-fed rats by measuring cortical neuronal responses to NMDA using in vivo NMDA micro-iontophoresis el ectrophysiology, and performance in the attentional set-shifting task.

Source: European Neuropsychopharmacology - November 22, 2017 Category: Psychiatry & Psychology Authors: Benjamin Gronier, Helene M. Savignac, Mathieu Di Miceli, Sherif M. Idriss, George Tzortzis, Daniel Anthony, Philip W.J. Burnet Source Type: research