[Correspondence] Prediction and prevention of tuberculosis in contacts

We read with great interest the Article by Matthew Saunders and colleagues on the use of a tuberculosis risk score.1 The authors developed their much-needed scoring system to predict the risk of tuberculosis development in contacts of patients with pulmonary tuberculosis. They also showed the feasibility of their scoring system in a population of contacts of patients with tuberculosis. However, their score slightly overestimated the risk in the high-risk group of the external validation cohort (the observed 2 ·5-year risk was 11·6% in the high-risk group in the derivation cohort vs 8·6% in the external validation cohort).
Source: The Lancet Infectious Diseases - Category: Infectious Diseases Authors: Tags: Correspondence Source Type: research