Prospects for developing an accurate diagnostic biomarker panel for low prevalence cancers

Conclusions: A highly accurate blood-based diagnostic panel can be developed from a reasonable number of individual serum biomarkers that are relatively weak classifiers when used singly. A panel constructed as described is advantageous in that a high level of specificity can be forced, accomplishing a prerequisite for screening asymptomatic populations for low-prevalence cancers.
Source: Theoretical Biology and Medical Modelling - Category: Biomedical Science Authors: Source Type: research