Capillarisin blocks prostate ‐specific antigen expression on activation of androgen receptor in prostate carcinoma cells

ConclusionsOur results indicated that Cap inhibited growth of LNCaP cells. Cap effectively suppressed androgen activation on AR‐mediated transactivation, which is AR‐dependent through AR degradation and dissociation of AR‐Hsp90 in prostate carcinoma cells.

Source: The Prostate - November 22, 2017 Category: Urology & Nephrology Authors: Ke ‐Hung Tsui, Ying‐Ling Chang, Tsui‐Hsia Feng, Chen‐Pang Hou, Yu‐Hsiang Lin, Pei‐Shan Yang, Bing‐Wei Lee, Horng‐Heng Juang Tags: ORIGINAL ARTICLE Source Type: research