Preclinical mouse solid tumour models: status quo, challenges and perspectives

Nature Reviews Cancer 17, 751 (2017). doi:10.1038/nrc.2017.92 Authors: Nicolas Gengenbacher, Mahak Singhal & Hellmut G. Augustin Oncology research in humans is limited to analytical and observational studies for obvious ethical reasons, with therapy-focused clinical trials being the one exception to this rule. Preclinical mouse tumour models therefore serve as an indispensable intermediate experimental model system bridging more reductionist in vitro
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Tags: Analysis Source Type: research