Enantioselective Copper ‐Catalyzed Alkylation of Quinoline N‐Oxides with Vinylarenes

AngewchemEnantioselective Copper ‐Catalyzed Alkylation of Quinoline N‐Oxides with Vinylarenes: An asymmetric copper ‐catalyzed alkylation of quinoline N‐oxides with chiral Cu–alkyl species, generated by migratory insertion of a vinylarene into a chiral Cu−H complex, is reported. A variety of quinoline...

Source: Organometallic Current - November 21, 2017 Category: Chemistry Tags: Alkylation Cu catalyzed Enantioselective Source Type: blogs