Cold Agglutinin Disease in Fibrolamellar Hepatocellular Carcinoma: A Rare Association with a Rare Cancer Variant

We report a case of a woman aged 18 years diagnosed with a welI -differentiated hepatocellular carcinoma of the fibrolamellar subtype, who was shown to have CAD also. Her general condition, including CAD, improved after targeted therapy with sorafenib for the hepatocellular carcinoma and only conservative measures for the CAD that consisted of avoidance of cold. In summary, although it is an extremely rare association and less common than lymphoproliferative disorders, CAD can be associated with solid tumors. Ann Saudi Med 2011: 31(2): 197-200PMID: 21293066 DOI: 10.4103/0256-4947.76409
Source: Annals of Saudi Medicine - Category: General Medicine Tags: ISSUE 2 Source Type: research