Association of interleukin-6 with aortic stiffness in  end-stage renal disease

Cardiovascular disease (CVD) is the leading cause of mortality in patients with chronic kidney disease (CKD). Aortic stiffness, a nontraditional risk factor, is associated with high rate of mortality in CKD. Using a CKD animal model with medial vascular calcification, we previously reported increased mRNA expression of interleukin-6 (IL-6), tumor necrosis factor (TNF), and interleukin-1 β (IL-1β) in calcified aorta. The aim of the study was to investigate the association between IL-6, TNF, IL-1β, and aortic stiffness in end-stage renal disease patients.

Source: Journal of the American Society of Hypertension - October 13, 2017 Category: Cardiology Authors: Marie-Pier Desjardins, Aboubacar Sidib é, Catherine Fortier, Fabrice Mac-Way, Karine Marquis, Sacha De Serres, Richard Larivière, Mohsen Agharazii Tags: Research Article Source Type: research