Alzheimer disease brain atrophy subtypes are associated with cognition and rate of decline

Conclusions: AD subtypes with phenotypes consistent with those observed with tau neuropathology can be identified in vivo with vMRI. An increased HV:CTV ratio was predictive of faster clinical decline in participants with AD who were clinically indistinguishable at baseline except for a greater dysexecutive presentation.

http://www.neurology.org/cgi/content/short/89/21/2176?rss=1

Source: Neurology - November 20, 2017 Category: Neurology Authors: Risacher, S. L., Anderson, W. H., Charil, A., Castelluccio, P. F., Shcherbinin, S., Saykin, A. J., Schwarz, A. J., For the Alzheimer's Disease Neuroimaging Initiative Tags: MRI, Alzheimer's disease ARTICLE Source Type: research