Serum neurofilament light in familial Alzheimer disease: A marker of early neurodegeneration
Conclusions:
Serum NfL concentration is increased in FAD prior to symptom onset and correlates with measures of disease stage and severity. Serum NfL may thus be a feasible biomarker of early AD-related neurodegeneration.
Source: Neurology - Category: Neurology Authors: Weston, P. S. J., Poole, T., Ryan, N. S., Nair, A., Liang, Y., Macpherson, K., Druyeh, R., Malone, I. B., Ahsan, R. L., Pemberton, H., Klimova, J., Mead, S., Blennow, K., Rossor, M. N., Schott, J. M., Zetterberg, H., Fox, N. C. Tags: Alzheimer's disease ARTICLE Source Type: research