Mechanobiology of YAP and TAZ in physiology and disease

Nature Reviews Molecular Cell Biology 18, 758 (2017). doi:10.1038/nrm.2017.87 Authors: Tito Panciera, Luca Azzolin, Michelangelo Cordenonsi & Stefano Piccolo A growing body of evidence suggests that mechanical signals emanating from the cell's microenvironment are fundamental regulators of cell behaviour. Moreover, at the macroscopic scale, the influence of forces, such as the forces generated by blood flow, muscle contraction, gravity and overall tissue rigidity (for
Source: Nature Reviews Molecular Cell Biology - Category: Cytology Authors: Tags: Review Source Type: research