Mechanical forces direct stem cell behaviour in development and regeneration

Nature Reviews Molecular Cell Biology 18, 728 (2017). doi:10.1038/nrm.2017.108 Authors: Kyle H. Vining & David J. Mooney Stem cells and their local microenvironment, or niche, communicate through mechanical cues to regulate cell fate and cell behaviour and to guide developmental processes. During embryonic development, mechanical forces are involved in patterning and organogenesis. The physical environment of pluripotent stem cells regulates their self-renewal
Source: Nature Reviews Molecular Cell Biology - Category: Cytology Authors: Tags: Review Source Type: research