Tuberculosis

Tuberculosis (TB) is currently the world's leading cause of infectious mortality. Imaging plays an important role in the management of this disease. The complex immune response of the human body to Mycobacterium tuberculosis results in a wide array of clinical manifestations, making clinical and radiological diagnosis challenging. 18F-FDG-PET/CT is very sensitive in the early detection of TB in most parts of the body; however, the lack of specificity is a major limitation. 18F-FDG-PET/CT images the whole body and provides a pre-therapeutic metabolic map of the infection, enabling clinicians to accurately assess the burden of disease.

Source: Seminars in Nuclear Medicine - November 16, 2017 Category: Nuclear Medicine Authors: Alfred O. Ankrah, Andor W.J.M. Glaudemans, Alex Maes, Christophe Van de Wiele, Rudi A.J.O. Dierckx, Mariza Vorster, Mike M. Sathekge Source Type: research