Lab blues and other humbug...

Teaching pharmacology: where one talks about selective drugs with specific effects that tell lovely, tidy stories about how this phenomenon is caused by that mechanism leading to the effective treatment of such-and-such a condition.Doing pharmacology: where one uses drugs that have multiple cellular targets - many of which are as yet ill-defined/unidentified - with completely different downstream effects depending on the cell type, species, protein expression levels and localization, temperature, stage in the lunar cycle, the NASDAQ index and a few other things besides, and that rarely have a remotely sensible chain of causality linking their cellular effects to the actual clinical outcome.
Source: Across the Bilayer - Category: Medical Scientists Source Type: blogs