An experimental study comparing the respiratory effects of tapentadol and oxycodone in healthy volunteers

ConclusionsIn this exploratory study we observed that both tapentadol and oxycodone produce respiratory depression. Tapentadol 100  mg but not 150 mg had a modest respiratory advantage over oxycodone 20 mg. Further studies are needed to explore how these results translate to the clinical setting.
Source: British Journal of Anaesthesia - Category: Anesthesiology Source Type: research