Lin28a enhances in vitro osteoblastic differentiation of human periosteum ‐derived cells

This study was to examine the impact of Lin28a on osteogenic phenotypes of human periosteum‐derived cells. Their phenotypes can be similar to those of mesenchymal stem cells. Our results suggest that the Lin28a gene enhances the osteoblastic differentiation of human periosteum‐derived cells. In addition, the Lin28a gene increases mitochondrial activity in human periosteum‐derived cells.

http://onlinelibrary.wiley.com/resolve/doi?DOI=10.1002%2Fcbf.3305

Source: Cell Biochemistry and Function - October 1, 2017 Category: Biochemistry Authors: Jin ‐Ho Park, Bong‐Wook Park, Young‐Hoon Kang, Sung‐Hoon Byun, Sun‐Chul Hwang, Deok Ryong Kim, Dong Kyun Woo, June‐Ho Byun Tags: RESEARCH ARTICLE Source Type: research