Comparison of haematology and biochemistry parameters in healthy South African infants with laboratory reference intervals

ConclusionsHaematology and biochemistry parameters in apparently healthy South African infants deviate frequently from national laboratory reference intervals, including abnormalities consistent with subclinical hypochromic microcytic anaemia. It is important that clinical laboratory reference intervals for children are derived locally, rather than being adopted from Caucasian norms in developed countries, because clinical trials of vaccines, drugs and diagnostics are increasingly conducted in sub‐Saharan Africa.This article is protected by copyright. All rights reserved.

Source: Tropical Medicine and International Health - November 1, 2017 Category: Tropical Medicine Authors: B. Schmidt, M. Tameris, H. Geldenhuys, A. Luabeya, E. Bunyasi, T. Hawkridge, J.B. McClain, H. Mahomed, T.J. Scriba, H. McShane, M. Hatherill Tags: Original Article Source Type: research