Accuracy of CoaguChek XS in Patients With Antiphospholipid Syndrome

Abstract: The CoaguChek XS meter is an international normalized ratio (INR) point-of-care (POC) monitor that has been shown to provide clinically acceptable accuracy. Because of a potential interaction between antiphospholipid antibodies and the reagent used in the prothrombin time INR assay, there is uncertainty as to the reliability of using POC INR monitors in patients with antiphospholipid syndrome (APLS). The study population consisted of 41 patients on warfarin therapy for either APLS (treatment group) or any other indication (control group). All patients had their INR analyzed by the CoaguChek XS meter and a central laboratory. Overall, the mean INR difference between the CoaguChek XS and laboratory in the APLS patients was 0.6772 (P
Source: Point of Care: The Journal of Near-Patient Testing and Technology - Category: Pathology Tags: Original Articles Source Type: research