Pediatric Orbital Primitive Neuroectodermal Tumors

Primitive neuroectodermal tumors (PNETs) are embryonal neoplasms that originate from the neural crest cells.1 They are a heterogenous group of malignant neuroepithelial tumors having small round cells that occur mostly in children and young adults. Initially, it was believed that central the nervous system was the most common site of PNETs. However, because they were seen outside of the central nervous system, PNETs were reclassified as central PNET and peripheral PNET. Orbital PNET is a subtype of peripheral PNET.2 Orbital PNET shows varying degrees of neural differentiation. Histopathology

Source: Journal of Pediatric Ophthalmology and Strabismus - November 14, 2017 Category: Opthalmology Authors: Tayyab Afghani, MS Source Type: research