Adding quantitative muscle MRI to the FSHD clinical trial toolbox

Conclusions: We show a strong correlation between quantitative muscle MRI and clinical outcome measures. Muscle MRI is able to detect muscle pathology before clinical involvement of the leg muscles. This indicates that quantitative leg muscle MRI is a promising biomarker that captures disease severity and motor functioning and can thus be included in the FSHD trial toolbox.

http://www.neurology.org/cgi/content/short/89/20/2057?rss=1

Source: Neurology - November 13, 2017 Category: Neurology Authors: Mul, K., Vincenten, S. C. C., Voermans, N. C., Lemmers, R. J. L. F., van der Vliet, P. J., van der Maarel, S. M., Padberg, G. W., Horlings, C. G. C., van Engelen, B. G. M. Tags: Outcome research, MRI, Muscle disease, Cohort studies ARTICLE Source Type: research