Postdoc: Univ of Minnesota Fungal Genomics

Postdoctoral Position – Fungal Genomics and Metabolomics University of Minnesota, St. Paul, MN Position description: A postdoctoral position focused on comparative genomics, metabolomics, and regulatory mechanisms of secondary metabolites in fungi is available in the Bushley lab. This project will focus on population genomics of fungi (Fusarium, Tolypocladium spp.) to investigate regulation and evolution of secondary metabolite genes, clusters, and metabolites. The project will adopt an interdisciplinary approach that integrates next-generation genome sequencing and assembly, comparative genomics, and RNA-Seq experiments with analyses of chemical products. Genome resequencing will examine the roles of structural variation, transposition, selection, genome methylation, and other evolutionary processes in driving the diversification of secondary metabolite genes and clusters. Strain specific differences in metabolite expression will be investigated under a variety of different media conditions and data will be integrated to develop and analyze metabolic and regulatory networks involved in controlling secondary metabolism. Minimum requirements: A Ph.D. in molecular biology and genetics, mycology, genomics, chemistry, biochemistry, or related fields. The ideal candidate will have existing skills in two or more of the following: experience in sequencing and analysis of next-generation sequence data, bioinformatics and comparative genomics, molecular biology, mass spectrometr...
Source: Fungal Genomes and Comparative Genomics - Category: Geneticists and Genetics Commentators Authors: Tags: postdoc bioinformatics evolution secondary metabolite Source Type: blogs