Forensic evaluation of reliability on STR typing in lung cancer

Short tandem repeats (STRs), alsoknownasmicrosatellites, are genomic DNA sequences that consist of repeatingunits (2 - 6 bp) [1]. In eukaryotic genomes, STRs are extensively distributed in non-codingregions and characterizedby co-dominant inheritance, high levels ofpolymorphisms, high reliability and goodreproducibility; thus making them effective for forensic analysis [1,2]. Assecond generation genetic marks, STRs are broadly used in forensics for personal identification and paternity testing [2 –4].

Source: Legal Medicine - November 11, 2017 Category: Forensic Medicine Authors: Peng Zhang, Ying Zhu, Yongguo Li, Shisheng Zhu, Ruoxiang Ma, Minzhu Zhao, Jianbo Li Source Type: research