Automated red blood cell exchange in preparation for filgrastim mobilization of autologous peripheral blood hematopoietic progenitor cells in a patient with sickle cell anemia
We report the use of automated red cell exchange in preparation for filgrastim mobilization in a patient with homozygous SCA. Red cell exchange was repeated just prior to high‐dose chemotherapy to mitigate the need for red cell transfusion during bone marrow reconstitution. The patient experienced no vaso‐occlusive phenomena throughout the entire episode of care and did not become iron overloaded. This approach should be considered for all patients with homozygous or compound heterozygous sickle cell disease who are candidates for auto‐HPC rescue therapy.
Source: Journal of Clinical Apheresis - Category: Hematology Authors: Yong Zhao, Jeffrey A. Bailey, Jeanne Linden, Patricia St. Pierre, Jan Cerny, Michelle Vauthrin, Mindy Greene, Robert Weinstein Tags: CASE REPORT Source Type: research
More News: Anemia | Cancer & Oncology | Chemotherapy | Filgrastim | Hematology | Iron | Neulasta | Neupogen | Sickle Cell Anemia