Bone mineral density and markers of bone turnover and inflammation in diabetes patients with or without a Charcot foot: An 8.5-year prospective case-control study

Charcot osteoarthropathy (Charcot foot, CF) is a rare but severe complication to diabetes mellitus and peripheral neuropathy, and is associated with increased morbidity and mortality.1 It manifests as an aseptic inflammation of bones and joints in the feet leading to progressive degeneration of the bone structures, which can cause deformity and ulceration.2 –5 The treatment consists of long-term off-loading, often accompanied by assisted wound healing and surgery.6,7

Source: Journal of Diabetes and Its Complications - November 10, 2017 Category: Endocrinology Authors: Rasmus Bo Jansen, Tomas M øller Christensen, Jens Bülow, Lene Rørdam, Per E. Holstein, Niklas Rye Jørgensen, Ole Lander Svendsen Source Type: research