Extranodal Rosai –Dorfman disease arising in the heart: clinical course and review of literature

Rosai –Dorfman disease (RDD), also known as sinus histiocytosis with massive lymphadenopathy, is a nonmalignant disease of unknown etiology. It may present as bilateral, massive, painless cervical lymphadenopathy; however, one third of the cases have extranodal involvement. Extranodal sites include soft tissue, skin, upper respiratory and gastrointestinal tracts, and central nervous system, with head and neck being the most common. Here we report a rare case of intracardiac RDD in a 46-year-old, African–American female who presented with worsening shortness of breath and fatigue for 7 weeks.

Source: Cardiovascular Pathology - July 4, 2017 Category: Cardiology Authors: Amin Heidarian, Ayesha Anwar, M.A. Haseeb, Raavi Gupta Tags: Clinical Case Report Source Type: research