Techniques & applications: Expanding the genetic toolbox for fungi

Nature Reviews Microbiology 15, 709 (2017). doi:10.1038/nrmicro.2017.141 Author: Andrea Du Toit Candida albicans is a common fungal pathogen of humans, but genetic interaction analysis has been limited in this diploid organism. To overcome the technical restrictions, Shapiro, Chavez et al. developed a CRISPR–Cas9-based gene drive array (GDA) platform that can efficiently generate homozygous double-gene
Source: Nature Reviews Microbiology - Category: Microbiology Authors: Tags: Research Highlight Source Type: research