Heterogeneity in retinoblastoma: a tale of molecules and models

Retinoblastoma, an intraocular pediatric cancer, develops in the embryonic retina following biallelic loss of RB1. However, there is a wide range of genetic and epigenetic changes that can affect RB1 resulting in...

Source: Clinical and Translational Medicine - November 9, 2017 Category: Internal Medicine Authors: Sonya Stenfelt, Maria K. E. Blixt, Charlotta All-Ericsson, Finn Hallb öök and Henrik Boije Tags: Review Source Type: research