Skeletal muscle signaling, metabolism, and performance during sprint exercise in severe acute hypoxia after the ingestion of antioxidants

This study showed that the ingestion of antioxidants before sprint exercise in severe acute hypoxia reduced the glycolytic rate and attenuated the increases of the AMP-to-ATP and the reduction of the NAD+-to-NADH.H+ ratios. This resulted in a modified muscle signaling response with a blunted Thr286-CaMKII but similar AMP-activated protein kinase phosphorylation responses in the sprints preceded by the ingestion of antioxidants.

Source: Journal of Applied Physiology - November 9, 2017 Category: Physiology Authors: Morales-Alamo, D., Guerra, B., Ponce-Gonzalez, J. G., Guadalupe-Grau, A., Santana, A., Martin-Rincon, M., Gelabert-Rebato, M., Cadefau, J. A., Cusso, R., Dorado, C., Calbet, J. A. L. Tags: RESEARCH ARTICLE Source Type: research