Remote ischemic preconditioning does not prevent acute mountain sickness after rapid ascent to 3,450 m

This study indicates that RIPC, performed immediately before passive ascent to 3,450 m, does not attenuate AMS and the magnitude of high-altitude pulmonary hypertension. NEW & NOTEWORTHY Remote ischemic preconditioning (RIPC) has been reported to improve neurologic and pulmonary outcome following an acute ischemic or hypoxic insult, yet the effect of RIPC for protecting from high-altitude diseases remains to be determined. The present study shows that RIPC, performed immediately before passive ascent to 3,450 m, does not attenuate acute mountain sickness and the degree of high-altitude pulmonary hypertension. Therefore, RIPC cannot be recommended for prevention of high-altitude diseases.

http://jap.physiology.org/cgi/content/abstract/123/5/1228?rss=1

Source: Journal of Applied Physiology - November 9, 2017 Category: Physiology Authors: Berger, M. M., Macholz, F., Lehmann, L., Dankl, D., Hochreiter, M., Bacher, B., Bärtsch, P., Mairbäurl, H. Tags: RESEARCH ARTICLE Source Type: research