Nickel ‐Catalyzed Cyanation of Aryl Chlorides and Triflates Using Butyronitrile: Merging Retro‐hydrocyanation with Cross‐coupling

We describe a nickel ‐catalyzed cyanation reaction of aryl (pseudo)halides that employs butyronitrile as a cyanating reagent instead of highly toxic cyanide salts. A dual catalytic cycle merging retro‐hydrocyanation...

Source: Organometallic Current - November 9, 2017 Category: Chemistry Tags: Al catalyzed Cyanation Ni Catalyzed Source Type: blogs