Remote Cooperative Group Strategy Enables Ligands for Accelerative Asymmetric Gold Catalysis

JacsRemote Cooperative Group Strategy Enables Ligands for Accelerative Asymmetric Gold Catalysis: An accelerative asymmetric gold catalysis is achieved for the first time via chiral ligand metal cooperation. An asymmetrically positioned remote amide group in the designed chiral binaphthyl-based ligand plays the essential role of a general base catalyst and selectively accelerates the cyclizations of 4-allen-1-ols into one prochiral allene face.

Source: Organometallic Current - November 9, 2017 Category: Chemistry Tags: Gold Catalysis Source Type: blogs