Cardiovascular Structure and Function in Children With Middle Aortic Syndrome and Renal Artery StenosisNovelty and Significance [Middle Aortic Syndrome]

Middle aortic syndrome (MAS) is a narrowing of the abdominal aorta, often in conjunction with renal artery stenosis (RAS). Structure and function of the cardiovascular system are not well understood. In a prospective cross-sectional study, 35 children with MAS or RAS or both (MAS/RAS) were compared with 140 age-, sex-, and body surface area–matched healthy children. Vascular assessment included carotid intima–media thickness and carotid distensibility using B-mode ultrasound and central and peripheral pulse wave velocities using applanation tonometry. Left ventricular structure and function were assessed by 2-dimensional and speckle-tracking echocardiography. Children with MAS or RAS were 12.5±3.0 years old at enrollment, and 50% were men. Carotid intima–media thickness (0.54±0.10 versus 0.44±0.05 mm; P

Source: Hypertension - November 8, 2017 Category: Cardiology Authors: Rawan K. Rumman, Cameron Slorach, Wei Hui, Mina Matsuda-Abedini, Valerie Langlois, Seetha Radhakrishnan, Armando J. Lorenzo, Joao Amaral, Luc Mertens, Rulan S. Parekh Tags: Hypertrophy, Hypertension, Echocardiography, Peripheral Vascular Disease, Stenosis Original Articles Source Type: research