Apelin Is a Negative Regulator of Angiotensin II-Mediated Adverse Myocardial Remodeling and DysfunctionNovelty and Significance [Heart]

In conclusion, pyr1-apelin-13 peptide pathway is a negative regulator of aging-mediated and Ang II–mediated adverse myocardial remodeling and dysfunction and represents a potential candidate to prevent and treat heart disease.

Source: Hypertension - November 8, 2017 Category: Cardiology Authors: Zhen-Zhou Zhang, Wang Wang, Hai-Yan Jin, Xueyi Chen, Yu-Wen Cheng, Ying-Le Xu, Bei Song, Josef M. Penninger, Gavin Y. Oudit, Jiu-Chang Zhong Tags: ACE/Angiotensin Receptors/Renin Angiotensin System, Fibrosis, Hypertrophy, Remodeling, Hypertension Original Articles Source Type: research