N-Bomb: a potent psychedelic stimulant

3.5 out of 5 stars 2C-I-NBOMe, an “N-bomb” that kills with “Smiles”. Toxicological and legislative aspects. Nikolaou P et al. Drug Chem Toxicol 2014 May 1 [Epub ahead of print] Abstract Despite the confusing title, this is a well done comprehensive review of 2C-I-NBOMe, an extremely  potent hallucinogenic stimulant that has been associated with deaths and severe toxicity. The NBOMe structure drugs have a 2-methoxybenzyl group attached to the nitrogen of a 2C psychedelic phenethylamine:   This substitution gives the drug enhanced activity at the 5-HT2A  serotonin receptor, a main target of many serotonergic agents such as LSD. Major common effects of 2C-I-NBOMe include tachycardia, agitation, visual and auditory hallucinations, hypertension and seizures. Street names for 2C-I-NBOMe include: N-Bomb 25I Bom-25 Cimbi-5 Legal Acid (it is, of course, neither legal nor LSD) Mr. Happy Solaris Smiles Smiley Paper This review is comprehensive and up-to-date, with 40 references (some as recent as this year). Worth reading for those with any interest in the topic.   Related posts: NBOME — it’s not your father’s LSD Case series: 7 patients with confirmed exposure to hallucinogenic stimulant 25I-NBOMe (“N-bomb”) 25I-NBOMe: a dangerous new hallucinogen  Case report: toxicity from designer drug 25I Seizures, hyperthermia, and serotonin syndrome following use of designer drug 2C-I (“Smiles”)  
Source: The Poison Review - Category: Toxicology Authors: Tags: Medical 25I 2C-I-NBOME hallucinogenic stimulant n-bomb smiles substituted phenethylamine Source Type: news