N-Bomb: a potent psychedelic stimulant
3.5 out of 5 stars
2C-I-NBOMe, an “N-bomb” that kills with “Smiles”. Toxicological and legislative aspects. Nikolaou P et al. Drug Chem Toxicol 2014 May 1 [Epub ahead of print]
Abstract
Despite the confusing title, this is a well done comprehensive review of 2C-I-NBOMe, an extremely potent hallucinogenic stimulant that has been associated with deaths and severe toxicity.
The NBOMe structure drugs have a 2-methoxybenzyl group attached to the nitrogen of a 2C psychedelic phenethylamine:
This substitution gives the drug enhanced activity at the 5-HT2A serotonin receptor, a main target of many serotonergic agents such as LSD.
Major common effects of 2C-I-NBOMe include tachycardia, agitation, visual and auditory hallucinations, hypertension and seizures.
Street names for 2C-I-NBOMe include:
N-Bomb
25I
Bom-25
Cimbi-5
Legal Acid (it is, of course, neither legal nor LSD)
Mr. Happy
Solaris
Smiles
Smiley Paper
This review is comprehensive and up-to-date, with 40 references (some as recent as this year). Worth reading for those with any interest in the topic.
Related posts:
NBOME — it’s not your father’s LSD
Case series: 7 patients with confirmed exposure to hallucinogenic stimulant 25I-NBOMe (“N-bomb”)
25I-NBOMe: a dangerous new hallucinogen
Case report: toxicity from designer drug 25I
Seizures, hyperthermia, and serotonin syndrome following use of designer drug 2C-I (“Smiles”)
Source: The Poison Review - Category: Toxicology Authors: Leon Tags: Medical 25I 2C-I-NBOME hallucinogenic stimulant n-bomb smiles substituted phenethylamine Source Type: news