Subjective cognitive decline and {beta}-amyloid burden predict cognitive change in healthy elderly

Conclusions: PiB+ individuals with SCD are at greatest risk of cognitive decline. Evidence for amyloid alone is not sufficient to indicate risk of rapid cognitive decline in healthy elderly. Effects of GDS on cognitive decline in nondepressed cohorts may be driven by SCD rather than subsyndromal depression.

http://www.neurology.org/cgi/content/short/89/19/2002?rss=1

Source: Neurology - November 6, 2017 Category: Neurology Authors: Vogel, J. W., Varga Dolezalova, M., La Joie, R., Marks, S. M., Schwimmer, H. D., Landau, S. M., Jagust, W. J. Tags: PET, Memory, Alzheimer's disease, Cognitive aging ARTICLE Source Type: research