Relative identifiability of anisotropic properties from magnetic resonance elastography

In conclusion, Young's modulii, shear modulii and damping can theoretically be well determined from MRE data, but Poisson's ratio is not as well determined and could be set to a reasonable value for biological tissue (close to 0.5).

Parameters that describe a transversely isotropic material are not equally identifiable from MRE displacement fields. This is shown using a finite‐element model update method, based on minimizing the differences between simulated and measured displacements, with simulated and experimental phantom MRE displacements. Identifiability was compared using quantitative measures calculated from the Hessian of the objective function. At the incompressible limit, Poisson's ratio is not identifiable. Additionally, the fibre Young's modulus is less identifiable than the transverse Young's modulus and shear modulus.

Source: NMR in Biomedicine - November 1, 2017 Category: Radiology Authors: Renee Miller, Arunark Kolipaka, Martyn P. Nash, Alistair A. Young Tags: SPECIAL ISSUE RESEARCH ARTICLE Source Type: research