Current and upcoming approaches to exploit the reversibility of epigenetic mutations in breast cancer

Rots and colleagues describe aberrant DNA methylation and histone modifications as two important classes of epigenetic mutations in breast cancer and review the preclinical and clinical epigenetic-based therapies currently being explored.

Source: Breast Cancer Research - July 29, 2014 Category: Cancer & Oncology Authors: Fahimeh FalahiMichel van KruchtenNadine MartinetGeke HospersMarianne Rots Source Type: research