Abstract A30: Identifying microenvironment-dependent vulnerabilities in multiple myeloma using CRISPRi

This study will pave the way to better understand the crosstalk between the tumor and its microenvironment and enable rational design of combination therapies to overcome drug resistance.Citation Format: Poornima Ramkumar, Jaime Tawney, Diego Acosta-Alvear, Martin Kampmann. Identifying microenvironment-dependent vulnerabilities in multiple myeloma using CRISPRi [abstract]. In: Proceedings of the AACR Precision Medicine Series: Opportunities and Challenges of Exploiting Synthetic Lethality in Cancer; Jan 4-7, 2017; San Diego, CA. Philadelphia (PA): AACR; Mol Cancer Ther 2017;16(10 Suppl):Abstract nr A30.

http://mct.aacrjournals.org/cgi/content/short/16/10_Supplement/A30?rss=1

Source: Molecular Cancer Therapeutics - October 2, 2017 Category: Cancer & Oncology Authors: Ramkumar, P., Tawney, J., Acosta-Alvear, D., Kampmann, M. Tags: Finding Synthetic Lethal Interactions through Functional Genomics: Poster Presentations - Proffered Abstracts Source Type: research