High-Affinity Internalizing Human scFv-Fc Antibody for Targeting FGFR1-Overexpressing Lung Cancer

This study reports a highly specific internalizing antibody fragment that can serve as a therapeutic targeting agent for efficient delivery of cytotoxic drugs into FGFR1-positive lung cancer cells. Mol Cancer Res; 15(8); 1040–50. ©2017 AACR.

Source: Molecular Cancer Research - August 1, 2017 Category: Cancer & Oncology Authors: Sokolowska-Wedzina, A., Chodaczek, G., Chudzian, J., Borek, A., Zakrzewska, M., Otlewski, J. Tags: Oncogenes and Tumor Suppressors Source Type: research