MELK and EZH2 Cooperate to Regulate Medulloblastoma Cancer Stem-like Cell Proliferation and Differentiation

This study demonstrates that the interaction occurring between MELK and EZH2 promotes self-proliferation and stemness, thus representing an attractive therapeutic target and potential candidate for diagnosis of medulloblastoma. Mol Cancer Res; 15(9); 1275–86. ©2017 AACR.

Source: Molecular Cancer Research - August 31, 2017 Category: Cancer & Oncology Authors: Liu, H., Sun, Q., Sun, Y., Zhang, J., Yuan, H., Pang, S., Qi, X., Wang, H., Zhang, M., Zhang, H., Yu, C., Gu, C. Tags: Signal Transduction Source Type: research