Unmetabolized Folic Acid, Tetrahydrofolate, and Colorectal Adenoma Risk

In conclusion, during the later follow-up period in which folic acid supplementation was previously seen to increase the risk of advanced and multiple adenomas, higher serum mF was associated with a higher risk of multiple and/or advanced adenomas, but no clear indication that UFA played a direct role. There were indications that higher mF was associated with reduced risk of serrated polyps. Cancer Prev Res; 10(8); 451–8. ©2017 AACR.

Source: Cancer Prevention Research - August 1, 2017 Category: Cancer & Oncology Authors: Rees, J. R., Morris, C. B., Peacock, J. L., Ueland, P. M., Barry, E. L., McKeown-Eyssen, G. E., Figueiredo, J. C., Snover, D. C., Baron, J. A. Tags: Research Articles Source Type: research